Discussions

Alzheimer's disease (AD) in vitro models provide a controlled environment to study amyloid-beta (Aβ) plaque formation, tau pathology, and neuroinflammation. These models utilize iPSC-derived neurons, astrocytes, and microglia to replicate disease mechanisms and test therapeutic strategies. Techniques such as 3D organoids, high-content screening, and biomarker analysis enable researchers to explore drug efficacy, synaptic dysfunction, and blood-brain barrier integrity. Advancing AD in vitro models enhances precision medicine, supporting innovative treatment development.